Soft tissue sarcoma is a rare type of cancer that begins in the tissues that connect, support and surround other body structures. This includes muscle, fat, blood vessels, nerves, tendons and the lining of your joints.
More than 50 subtypes of soft tissue sarcoma exist. Some types are more likely to affect children, while others affect mostly adults. These tumors can be difficult to diagnose because they may be mistaken for many other types of growths.
Soft tissue sarcoma can occur anywhere in your body, but the most common types occur in the arms and legs, and in the abdomen. Surgical removal is the most common treatment, although radiation and chemotherapy also may be recommended — depending on the size, type, location and aggressiveness of the tumor.

The soft tissues of the body include the muscles, tendons (bands of fiber that connect muscles to bones), fat, blood vessels, lymph vessels, nerves, and tissues around joints. Adult soft tissue sarcomas can form almost anywhere in the body, but are most common in the head, neck, arms, legs, trunk, abdomen, and retroperitoneum.

Types

  • Angiosarcoma
  • Dermatofibrosarcoma protuberans
  • Epithelioid sarcoma
  • Gastrointestinal stromal tumor (GIST)
  • Kaposi's sarcoma
  • Leiomyosarcoma
  • Liposarcoma
  • Malignant peripheral nerve sheath tumors
  • Myxofibrosarcoma
  • Pleomorphic sarcoma
  • Rhabdomyosarcoma
  • Solitary fibrous tumor
  • Synovial sarcoma
  • Undifferentiated pleomorphic sarcoma

Symptoms

A soft tissue sarcoma may not cause any signs and symptoms in its early stages. As the tumor grows, it may cause:

  • A noticeable lump or swelling
  • Pain, if a tumor presses on nerves or muscles